Product Compliance
filing/registration/consulting/training

recently,Brazilian National Health Supervision Agency Anvisa officially announce Cancel all items containing TPO (Diphenyl(2,4,6-trimethylbenzoyl) phosphine oxide)andDMPT N,N-dimethyl-p-toluidine Registration of cosmetics with ingredients.The affected products exceed 500 a,Covering nail art phototherapy adhesive Phototherapy nail polish and other multiple categories.
This means These products will be sold within BrazilProduction is no longer allowed Selling or using.
01|Regulatory background From disabling to complete delisting,only use 90 day
October 2025,Anvisa release RDC 995/2025,Clearly define TPO and DMPT Listed as a prohibited substance,And set it up 90 Transition period.After the transition period ends,Products containing these two ingredients Cannot continue to sell,Existing products on the market must Stop using and recall,Product registration will be directly cancelled.
2026 year 3 moon,Anvisa Execute as planned,release RE 1.146/2026,Formally announcing the list of products whose registration has been cancelled.
02|Why ban it TPO and DMPT The health risks have been internationally confirmed
Although widely used in the nail art industry,But international research has identified its health risks
DMPT N,N-Dimethyl p-toluidine Classified as a possible carcinogen,Long term exposure may increase cancer risk
TPO photoinitiator Classified as a reproductive toxic substance,May affect fertility,Especially for long-term contact groups such as nail technicians,Higher risk.
Therefore,Anvisa express The prohibition measures are aimed at protecting the health of consumers and professional nail technicians.
03|Synchronize with the European Union Brazil fully aligns with international safety standards
04|Conclusion Regulatory upgrade,It is the beginning of industry evolution