Q&A on the Filing of Ordinary Cosmetics by Beijing Food and Drug Administration Thirty ninth issue
What is the purpose of cosmetics anti-corrosion challenge testing
answer Cosmetic anti-corrosion challenge testing refers to testing under certain conditions,Artificially contaminating a certain amount of bacteria, fungi, and other microorganisms into cosmetics,Simulate the possible contamination of cosmetics,Detect the amount of surviving bacteria at regular intervals,A test for evaluating the efficacy of cosmetic preservative systems based on changes in the amount of surviving bacteria.Cosmetic anti-corrosion challenge testing helps clarify the impact of cosmetic anti-corrosion systems on cosmetic production Storage The protective effect of microorganisms that may be introduced during use,Provide assurance for the safe use of cosmetics by consumers.
When the cosmetics registrant conducts cosmetics anti-corrosion challenge testing,Is it necessary to follow Guidelines for Testing and Evaluation Techniques of Cosmetics Anti corrosion Challenge Conduct research
answer Cosmetic registrant The registrant can choose based on their actual needs and circumstances,Select industry standards international standard asISO 11930 Or self built methods,Comprehensively evaluate the effectiveness of the product's anti-corrosion system. Guidelines for Testing and Evaluation Techniques of Cosmetics Anti corrosion Challenge Is it a non mandatory reference document,Cosmetic registrant The registrant can refer to when conducting anti-corrosion challenge testing Guidelines for Testing and Evaluation Techniques of Cosmetics Anti corrosion Challenge Or conduct relevant research through other methods.
except Guidelines for Testing and Evaluation Techniques of Cosmetics Anti corrosion Challenge Outside,What are the relevant standards and methods that can be referenced for cosmetic anti-corrosion challenge testing
answer (1)ISO 11930-2019 Cosmetics - Microbiology - Evaluation of the antimicrobial protection of a cosmetic product
(2)AOAC 998.10-2009 Efficacy of Preservation of Non-Eye Area Water-Miscible Cosmetic and Toiletry Formulations
(3)USP 43-NF 38<51> Antimicrobial effectiveness testing
(4) Pharmacopoeia of the People's Republic of China 2020Year Edition Four General Rules1121Antibacterial efficacy test method
(5)T/SHRH 017-2019 Cosmetic anti-corrosion challenge test
(6)T/GDCDC 010-2019 Challenge testing method for cosmetics anti-corrosion
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What role does neutralizing agent play in cosmetic anti-corrosion challenge testing
answer Neutralizers can be added to cosmetics and microbial mixtures,Reagents for eliminating the inhibitory or bactericidal effects of antibacterial or bactericidal ingredients in cosmetics on microorganisms,It plays an important role in cosmetics anti-corrosion challenge testing.Neutralizers can avoid or reduce the potential interference of antibacterial or bactericidal ingredients in cosmetics on test results,To detect microorganisms that survive in cosmetics as much as possible,Thus accurately reflecting the actual pollution situation of microorganisms,Ensure the accuracy of test results.
How to choose and use neutralizing agents in cosmetics anti-corrosion challenge testing
answer Cosmetic registrant The registrant may choose the appropriate neutralizing agent based on the actual product formula,Common neutralizing agents includeSCDLPLiquid culture medium Eugon LT 100 broth D/EZhonghe meat soup improvementLetheenMeat soup, etc.If the neutralization effect verification is not passed,Consider replacing the neutralizing agent or increasing the amount of neutralizing agent used.When choosing to increase the dosage of neutralizing agent as a treatment method,Attention should be paid to gradually increasing the amount of neutralizing agent used,And it is recommended that the dilution ratio of the sample with neutralizing agent should not exceed100times.
